![]() ![]() Cordyceps species have diverse pharmaceutical properties and are commonly used to promote longevity and relieve fatigue along with immunomodulating, anti-oxidant, anti-tumor, anti-cancer, anti-metastatic, anti-inflammatory, anti-oxidative, antibiotic, hepatoprotective, nephroprotective, hypoglycemic, and hypocholesterolemic effects in humans. Cordyceps host range is very wide but predominant on two orders Coleoptera and Lepidoptera. ![]() Cordyceps attacks mainly the insect larvae, with few reports on pupa and adults the fungus invades and gradually replaces the host tissue by its mycelium. xuefengensis by Yao people.Ĭordyceps are entomopathogenic fungi, which include about 400 species, have cosmopolitan distribution, and are dominant and abundantly found in humid temperate and tropical forests. The application of this work will provide reliable fundamental pharmacological substances for the use of O. This is the first detailed comparative analysis of the in vitro anticancer activity and chemical ingredients between O. xuefengensis and 8 compounds were reported in caterpillar fungus for the first time. A total of 67 compounds were reported in O. Among these compounds, 68 compounds commonly existed in both O. A total of 82 compounds and 101 compounds were identified or tentatively characterized in the bioactive fractions of O. These two bioactive fractions were analyzed by UPLC–ESI–Q–TOF–MS/MS technology. sinensis have significant in vitro anti‐cancer activity. The results show that ethyl acetate fractions of O. An MTT assay was used to evaluate the in vitro anticancer activities of different fractions from O. The aims of the present study are to evaluate the anticancer activity and to qualitatively analyze the potential bioactive chemical constituents of O. ![]() Ophiocordyceps xuefengensis, a new species of caterpillar fungus, has been identified as the sister taxon of Ophiocordyceps sinensis. sinensis and has a large genome but with a heterothallic mating system. Ophiocordyceps robertsii is a close relative of O. sinensis, as well as capabilities to explore the pharmaceutical potential in a species endemic to Australia and New Zealand. These resources provide a new opportunity for understanding the evolution of the expanded genome in the homothallic species O. The mating type locus was characterized, indicating a heterothallic arrangement whereby each strain has an idiomorphic region of two ( MAT1-2-1, MAT1-2-2 ) or three ( MAT1-1-1, MAT1-1-2, MAT1-1-3 ) genes flanked by the conserved APN2 and SLA2 genes. This species has a large genome expansion, as also occurred in O. robertsii strains were isolated into culture and high coverage draft genome sequences obtained and analyzed. sinensis, but little is known about this species despite being also of historical significance. Ophiocordyceps robertsii, found in Australia and New Zealand, has been proposed to be a close relative to O. One of the best known of these is Ophiocordyceps sinensis, which is used in Chinese medicine and its overharvesting threatens sustainability hence, alternative sources are being sought. The fungal genus Ophiocordyceps contains a number of insect pathogens. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |